Best Big Pine Key (FL) Hotels With 18+ Check-In (Updated January 2026)

Welcome to the mesmerizing world of Big Pine Key, Florida! An unspoiled gem tucked away in the Florida Keys, Big Pine Key is the ideal destination for adventure seekers, nature lovers, and those in search of a tranquil retreat. This island paradise is renowned for its unique wildlife, crystal-clear waters, and exotic marine life.

As you explore Big Pine Key, you'll find your senses captivated by the lush, tropical greenery, the gentle whisper of the ocean waves, and the spectacular sunsets that set the sky ablaze each evening. The island is home to the National Key Deer Refuge, a natural habitat for the endangered Key deer. Snorkeling and diving enthusiasts will be thrilled at the sight of the colorful coral reefs and the abundance of marine life at Looe Key National Marine Sanctuary.

Big Pine Key offers an array of outdoor activities to cater to your adventurous spirit. Whether you're in the mood for fishing, boating, or simply enjoying a picnic under the swaying palm trees, this island paradise has it all. Venture into the unexplored, immerse yourself in the enchanting natural beauty and create unforgettable memories at Big Pine Key, Florida.

Below is a list of hotels and motels in Big Pine Key that allow reservations for guests under 21, including those aged 18, 19, and 20. From cheap options to more adult-focused accommodations, there's a variety of places to rent that fit your needs and preferences!

Please note that hotel policies regarding the minimum check-in age in Big Pine Key can change at any time. While we aim to keep our information updated, we recommend confirming the minimum age requirement with the hotel or motel before making a reservation.