Best Muscatine (IA) Hotels With 18+ Check-In (Updated February 2026)

Welcome to Muscatine, Iowa, a hidden gem in the heart of America! This vibrant city, nestled along the mighty Mississippi River, offers an unforgettable blend of stunning landscapes, rich history, and exciting attractions that appeal to young travelers.

Whether you're an outdoor enthusiast or a culture vulture, Muscatine has something for everyone. From exploring its picturesque parks and trails to diving into its intriguing past at various museums, your days here will be packed with adventure and learning. And as the sun sets, immerse yourself in the city's spirited nightlife, with its eclectic range of bars, breweries, and live music venues!

Don't miss the chance to sample Muscatine's famed local produce, especially its world-renowned melons and sweet corn, and a host of delicious delicacies at downtown eateries. Above all, it's the friendly locals that truly make this city shine, their warm Midwestern hospitality making every visitor feel right at home.

Below is a list of hotels and motels in Muscatine that allow reservations for guests under 21, including those aged 18, 19, and 20. From cheap options to more adult-focused accommodations, there's a variety of places to rent that fit your needs and preferences!

Please note that hotel policies regarding the minimum check-in age in Muscatine can change at any time. While we aim to keep our information updated, we recommend confirming the minimum age requirement with the hotel or motel before making a reservation.