Best Santee (SC) Hotels With 18+ Check-In (Updated January 2026)

Below is a list of hotels and motels in Santee that allow reservations for guests under 21, including those aged 18, 19, and 20. From cheap options to more adult-focused accommodations, there's a variety of places to rent that fit your needs and preferences!

Please note that hotel policies regarding the minimum check-in age in Santee can change at any time. While we aim to keep our information updated, we recommend confirming the minimum age requirement with the hotel or motel before making a reservation.

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Top 18+ Hotels in Santee

Yes, you can generally book a hotel room at 18 in Santee, but many hotels have a minimum check-in age of 21. Policies vary, so it's best to check the hotel's website or call directly for confirmation.

Cities in the Same State as Santee for 18-Year-Old Hotel Check-Ins

B Beaufort C Charleston Columbia Conway F Florence G Greenville H Hardeeville Hilton Head Island I Isle of Palms K Kiawah Island L Laurens M Mount Pleasant Murrells Inlet Myrtle Beach N North Augusta North Charleston North Myrtle Beach O Orangeburg S Santee Spartanburg Sumter Surfside Beach T Travelers Rest W Walterboro